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Meet the HOD


Prof Sharon Prince obtained a BSc degree with majors in Chemistry and Microbiology, a BSc (Hons) degree with distinction in Cell Biology and a PhD in Cell Biology, all from UCT. She was a Welcome Trust Postdoctoral Fellow at the Marie-Curie Research Institute in the United Kingdom. Prof Prince joined UCT’s Department of Human Biology as a Lecturer in 2005 and was promoted ad hominem to Senior Lecturer in 2008, Associate Professor in 2012 and Full Professor in 2016.

Prof Prince is a Professor in Cell Biology and leads a large and very productive research group in the area of novel therapeutic interventions and drug targets for the treatment of cancer. Prof Prince’s research focusses particularly on understanding the role of the TBX2/3 transcription factors in several cancers, the use of organometallic compounds as cancer drugs, and the repurposing of existing non-cancer drugs for cancer therapies. She has published several seminal papers on the role and regulation of the transcription factors TBX2 and TBX3 in cancer and is internationally recognized as a pioneer and authority in this field. She collaborates with leading international researchers, publishes in top journals in the field, is invited to give lectures at national and international meetings and is a regular reviewer for journals and funding bodies. Integral to Prof Prince’s research is her highly effective training of postgraduate students and postdoctoral fellows. Her MSc and PhD students and postdoctoral researchers frequently win prizes at national and international research meetings.

Prof Prince is a member of the Academy of Science of South Africa (ASSAf). She has been recognised by UCT as one of its leading women innovators, commending her excellence in innovative research and as role model in science. Prof Prince received the Oppenheimer Memorial Trust Fellowship in 2019 and 2011, the Harry Crossley Senior Clinical Fellowship in 2010, and was appointed the Director of a breast cancer consortium in 2012.

Prof Prince has established a strong and vibrant research network with collaborators at international institutions including the University of Oxford in the United Kingdom; Boston University in the USA; the University Côte d’Azur Nice, CNRS, Universite Paris-Saclay, PSL Research University in France, International Centre for Genetic Engineering and Biotechnology (ICGEB) in Italy, SRM Institute of Science and Technology, Chennai, India, as well as the University of São Paulo Instituto and Câncer do Estado de São Paulo Octavio Frias de Oliveira (ICESP) in Brazil.